EIF2B
eIF2B is a protein complex found in eukaryotes. It is the guanine nucleotide exchange factor for the eukaryotic initiation factor 2 and therefore converts the inactive eIF2-GDP to the active eIF2-GTP. This activation is hindered by phosphorylation of the alpha subunit of eIF2, which leads to a stable eIF2α-P-GDP-eIF2B complex and therefore inhibits translation initiation. Human genes which encode eIF-2B proteins include: EIF2B1 – alpha subunit (26kDa) EIF2B2 – beta subunit (39kDa) EIF2B3 – gamma subunit (58kDa) EIF2B4 – delta subunit (67kDa) EIF2B5 – epsilon subunit (82kDa)
How these numbers are calculated
Each number comes from the Pythagorean system applied to the title “EIF2B”: the Destiny number uses all letters, the Heart’s Desire uses vowels only, and the Dream number uses consonants only. Letter values are summed and reduced until a single digit or master number (11, 22, 33) is reached.